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Test ID: FBL Fungal Culture, Blood

Reporting Name

Fungal Culture, Blood

Useful For

Diagnosis and treatment of the etiologic agents of fungemia

 

Select patient population that presents with signs and symptoms of sepsis, especially fever of unknown origin

Clinical Information

Due to the high mortality rate from fungemia, the expeditious detection and identification of fungi from the patient's blood can have great diagnostic prognostic importance. Risk factors for fungemia include, but are not limited to, extremes of age, immunosuppression, and those individuals with burns or indwelling intravascular devices.

Interpretation

Positive cultures of yeast and filamentous fungi are reported with the organism identification.

 

Positive cultures are usually an indication of infection and are reported as soon as detected. Correlation of culture results and the clinical situation is required for optimal patient management. A final negative report is issued after 30 days of incubation.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
D2F D2 Fungal Sequencing Identification No, (Bill Only) No
FUNA Fungal Ident Panel A No, (Bill Only) No
FUNB Fungal Ident Panel B No, (Bill Only) No
LCCI Ident Rapid PCR Coccidioides No, (Bill Only) No
LCHB Id, Histoplasma/Blastomyces PCR No, (Bill Only) No
RMALF Id MALDI-TOF Mass Spec Fungi No, (Bill Only) No
RMALY Id MALDI-TOF Mass Spec Yeast No, (Bill Only) No

Testing Algorithm

When this test is ordered, the reflex test may be performed and charged.

Analytic Time

30 days/positive cultures reported as soon as detected.

Day(s) and Time(s) Performed

Monday through Sunday; Varies

Clinical Reference

1. Reimer LG, Wilson ML, Weinstein MP: Update on detection of bacteremia and fungemia. Clin Microbiol Rev 1997;10:444-465

2. Procop GW, Cockerill FR III, Vetter EA, et al: Performance of five agar media for recovery of fungi from isolator blood cultures. J Clin Microbiol 2000;38(10):3827-3829

Method Name

Conventional broth culture technique with identification by macroscopic and microscopic morphology, nucleic acid hybridization probes, D2 rDNA gene sequencing, real-time polymerase chain reaction (rtPCR), or MALDI-TOF mass spectrometry. Dimorphic pathogen identification is confirmed using molecular methods (ie, nucleic acid hybridization probes, D2 rDNA gene sequencing, rtPCR or MALDI-TOF mass spectrometry).

Specimen Type

Whole blood


Specimen Required


Container/Tube:

Preferred: Green top (heparin)

Acceptable: SPS/Isolator tube

Specimen Volume: 10-30 mL

Collection Instructions: Send specimen in original tube.


Specimen Minimum Volume

5 mL
Pediatric: 1.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole blood Ambient (preferred) 7 days
  Refrigerated  7 days

Reference Values

Negative

If positive, notification is made as soon as the positive culture is detected or identified.

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

87015-Concentration (any type) for infectious agents

87103-Blood

87106-Id MALDI-TOF Mass Spec Yeast (if appropriate)

87107-Id MALDI-TOF Mass Spec Fungi (if appropriate)

87106-Yeast identification panel D (if appropriate)87107-Fungal identification panel A (if appropriate)      

87107-Fungal identification panel B (if appropriate)

87150-Identification rapid PCR coccidioides (if appropriate)

87150 x 2- Identification Histoplasma/Blastomyces, PCR (if appropriate)

87153- D2 fungal sequencing identification (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FBL Fungal Culture, Blood 601-5

 

Result ID Test Result Name Result LOINC Value
FBL Fungal Culture, Blood 601-5

Forms

If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.

Mayo Clinic Laboratories | Neurology Catalog Additional Information:

mml-CNS-Infections, mml-Pediatric, mml-Spinal-Cord