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Test ID: SBL Blastomyces Antibody Immunodiffusion, Serum

Reporting Name

Blastomyces Ab, Immunodiffusion, S

Useful For

Detection of antibodies in serum specimens in patients with blastomycosis

Clinical Information

The dimorphic fungus, Blastomyces dermatitidis, causes blastomycosis. When the organism is inhaled, it causes pulmonary disease-cough, pain, and hemoptysis, along with fever and night sweats. It commonly spreads to the skin, bone, or internal genitalia where suppuration and granulomas are typical. Occasionally, primary cutaneous lesions after trauma are encountered; however, this type of infection is uncommon.


A positive result is suggestive of infection, but the results cannot distinguish between active disease and prior exposure.


Routine culture of clinical specimens (eg, respiratory specimen) is recommended in cases of suspected, active blastomycosis.

Report Available

2 to 5 days

Day(s) Performed

Monday, Tuesday through Friday

Clinical Reference

1. Kaufman L, Kovacs JA, Reiss E: Clinical immunomycology. In: Rose NL, Conway-de Macario E, Folds JD et al. eds. Manual of Clinical and Laboratory Immunology. ASM Press; 1997:588-589

2. Gauthier GM, Klein BS: Blastomycosis. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Elsevier; 2020:3177-3189

Method Name


Specimen Type


Specimen Required


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values


Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
SBL Blastomyces Ab, Immunodiffusion, S 5058-3


Result ID Test Result Name Result LOINC Value
15125 Blastomyces Immunodiffusion 5058-3


If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.

Mayo Clinic Laboratories | Neurology Catalog Additional Information:

mml-CNS-Infections, mml-Pediatric