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HelpTest ID: SPSM Morphology Evaluation (Special Smear), Blood
Reporting Name
Morphology Eval (special smear)Useful For
Detecting disease states or syndromes of the white blood cells, red blood cells, or platelet cell lines of a patient's peripheral blood
Clinical Information
Under normal conditions, the morphology and proportion of each blood cell type is fairly consistent in corresponding age groups. The morphology and proportion of each blood cell type may change in various hematologic diseases. Differential leukocyte count and special smear evaluation is helpful in revealing the changes in morphology or proportion of each cell type in the peripheral blood.
Interpretation
The laboratory will provide an interpretive report of percentage of white cells and, if appropriate, evaluation of white cells, red cells, and platelets.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| DIFFS | Morphology Eval (Special Smear) | No | Yes |
| SPSM_ | Special Smear | No | Yes |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| PINTP | Peripheral Smear Interpretation | No | No |
| CBCN | CBC without Differential | Yes | No |
Testing Algorithm
If clinically abnormal results are identified by microscopic examination, a peripheral blood smear review is performed by a Hematopathologist at an additional charge.
If patient has not had a complete blood cell count in the last 3 days, one will be performed at an additional charge.
Report Available
1 dayDay(s) Performed
Sunday through Saturday
Clinical Reference
1. Kjeldsberg CR, eds. Practical Diagnosis of Hematologic Disorders. 5th ed. American Society of Clinical Pathologists; 2010
2. Pozdnyakova O, Connell NT, Battinelli EM, Connors JM, Fell G, Kim AS. Clinical significance of CBC and WBC morphology in the diagnosis and clinical course of COVID-19 infection. Am J Clin Pathol.. 2021 Feb 11;155(3):364-375. doi: 10.1093/ajcp/aqaa231
Method Name
Manual-Microscopic Examination of Cells
Specimen Type
Whole bloodNecessary Information
Clinician should provide indication for performing test.
Specimen Required
Collection Container/Tube: 2 slides
Specimen Volume: 2 unstained, well prepared peripheral blood smears
Collection Instructions: Smears made from blood obtained by either a lavender top (EDTA) tube or finger stick specimen
Specimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole blood | Ambient (preferred) | CARTRIDGE | |
| Refrigerated | CARTRIDGE | ||
Special Instructions
Reference Values
1-3 years
Neutrophils/bands: 22-51%
Lymphocytes: 37-73%
Monocytes: 2-11%
Eosinophils: 1-4%
Basophils: 0-2%
Metamyelocytes: 0%
Myelocytes: 0%
4-7 years
Neutrophils/bands: 30-65%
Lymphocytes: 29-65%
Monocytes: 2-11%
Eosinophils: 1-4%
Basophils: 0-2%
Metamyelocytes: 0%
Myelocytes: 0%
8-13 years
Neutrophils/bands: 35-70%
Lymphocytes: 23-53%
Monocytes: 2-11%
Eosinophils: 1-4%
Basophils: 0-2%
Metamyelocytes: 0%
Myelocytes: 0%
Adults
Neutrophils/bands: 50-75%
Lymphocytes: 18-42%
Monocytes: 2-11%
Eosinophils: 1-3%
Basophils: 0-2%
Metamyelocytes: <1%
Myelocytes: <0.5%
An interpretive report will be provided.
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
85007
85060-(if appropriate)
85027-(if appropriate)
88184-(If appropriate)
88185-(If appropriate)
88187-(if appropriate)
88188-(if appropriate)
88189-(if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SPSM | Morphology Eval (special smear) | 14869-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| SEGBA | Neutrophilic Segs and Bands | 23761-0 |
| LYMPH | Lymphocytes | 26478-8 |
| MONOC | Monocytes | 26485-3 |
| EOS | Eosinophils | 714-6 |
| BASO | Basophils | 707-0 |
| META | Metamyelocytes | 740-1 |
| MYEL | Myelocytes | 749-2 |
| PROMY | Promyelocytes | 783-1 |
| UBLS | Blasts | 709-6 |
| PLSM | Plasma Cells | 79426-3 |
| M_KR | Megakaryocytes | 19252-6 |
| NUCL | Nucleated RBC | 19048-8 |
| FRAGC | Fragile Cells | 34992-8 |
| BL_PR | Blasts and Promonocytes | 709-6 |
| MANC | Manual Absolute Neutrophil Count | 753-4 |
| INT01 | Interpretation | 59466-3 |
| REV96 | Reviewed by: | 18771-6 |
mml-Behavioral, mml-Movement-Disorders, mml-Pediatric